WHO preferred product characteristics for vaccines against enterotoxigenic Escherichia coli

Overview

Diarrhoeal diseases are among the leading causes of morbidity and mortality worldwide. Among children younger than 5 years, it is estimated that diarrhoea is responsible for about 446 000 deaths (390 894– 504 613), which are geographically concentrated in sub-Saharan Africa and South Asia. 

WHO preferred product characteristics (PPCs) provide strategic guidance on WHO preferences for new vaccines, particularly from a LMIC perspective.