The nutritional & biological significance of saponins

J Milgate, DCK Roberts - Nutrition Research, 1995 - Elsevier
The association between saponin intake and cholesterol metabolism is reviewed in this
article. Consumption of foods with high saponin concentrations by humans and its potential
danger, is also discussed. Saponins have been shown to demonstrate hemolytic action
towards red blood cells, and can be toxic if given intravenously but not orally. The majority of
saponins form insoluble complexes with 3-β-hydroxysteroids and are known to interact with
and form large ixed micelles with bile acids and cholesterol. Thus in rats, saponin intake has …