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Prefrontal cortical regulation of REM sleep
Rapid eye movement (REM) sleep is accompanied by intense cortical activity, underlying its wake-like electroencephalogram. The neural activity...
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Heritability of REM sleep neurophysiology in adolescence
Alterations of rapid eye movement (REM) sleep have long been observed in patients with psychiatric disorders and proposed as an endophenotype—a link...
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Clinical subtypes in patients with isolated REM sleep behaviour disorder
Patients with Parkinson’s disease (PD) show a broad heterogeneity in clinical presentation, and subtypes may already arise in prodromal disease...
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A cluster of mesopontine GABAergic neurons suppresses REM sleep and curbs cataplexy
Physiological rapid eye movement (REM) sleep termination is vital for initiating non-REM (NREM) sleep or arousal, whereas the suppression of...
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Altered parasympathetic activity during sleep and emotionally arousing wakefulness in frequent nightmare recallers
Nightmare disorder is characterized by dysfunctional emotion regulation and poor subjective sleep quality reflected in pathophysiological features...
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Sleep and Sleep Disorders
Humans spend one-third of their lives sleeping, indicating the vital importance of sleep for health and survival. The specific characteristics of... -
Sleep and Sleep–Wake Disorders
Sleep is an essential physiological function. Obtaining an adequate duration of sleep at the appropriate time is important for overall physical and... -
Chronic antidepressant treatment rescues abnormally reduced REM sleep theta power in socially defeated rats
The effects of chronic antidepressant (AD) treatment on sleep disturbances in rodent chronic stress models have not been thoroughly investigated....
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Sleep
Disturbances of sleep are detrimental to the quality of life for the aging individual. Sleep disorder studies among adults above age 50 found that... -
Study on the circadian rhythm and sleep state characteristics of patients with acute cerebral infarction accompanied by sleep-breathing disorders
There is limited research on the circadian rhythm and sleep state in patients with acute cerebral infarction (ACI) accompanied by sleep-breathing...
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The intersection of sleep and synaptic translation in synaptic plasticity deficits in neurodevelopmental disorders
Individuals with neurodevelopmental disorders experience persistent sleep deficits, and there is increasing evidence that sleep dysregulation is an...
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Sleep and Sleep Disorders
Humans spend one-third of their lives sleeping, indicating the vital importance of sleep for health and survival. The specific characteristics of... -
Differential effects of the stress peptides PACAP and CRF on sleep architecture in mice
Stress produces profound effects on behavior, including persistent alterations in sleep patterns. Here we examined the effects of two prototypical...
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Autonomic Dysfunction in Sleep Disorders
The autonomic nervous system (ANS) main function is the maintenance of body homeostasis and the promotion of adaptation against external changes.... -
Sleep Disorders: Identifying Biomarkers and Clinical Applications
In recent years, there was a surge in interest for biomarkers in sleep disorders. In this chapter we will focus on biomarkers with potential use in... -
Polysomnographic characteristics of sleep in adults with and without physician-diagnosed atopic dermatitis: results from the Study of Health in Pomerania
PurposeTo analyze sleep characteristics as measured with polysomnography (PSG) in adults from the general population with and without...
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REM Sleep Deprivation Impairs Learning and Memory by Decreasing Brain O-GlcNAc Cycling in Mouse
Rapid eye movement (REM) sleep is implicated learning and memory (L/M) functions and hippocampal long-term potentiation (LTP). Here, we demonstrate...
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Cardiovascular Implications of Sleep Disorders Beyond Sleep Apnea
Purpose of reviewSleep is crucial for human health and life. There is still limited attention to the association between sleep disorders beyond sleep...
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Disrupted sleep-wake regulation in the MCI-Park mouse model of Parkinson’s disease
Disrupted sleep has a profound adverse impact on lives of Parkinson’s disease (PD) patients and their caregivers. Sleep disturbances are exceedingly...
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Sleep-Wake Disorders
An important part of geriatric psychiatry, and mental health in general, is sleep. Age-related physiological and pathological changes are underlying...