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Experimental validation in a neutron exposure frame of the MINAS TIRITH for cell damage simulation

Yann Thibaut , Geraldine Gonon , Juan Martinez Guerrero , Michael Petit , Richard Babut , et al.
Physics in Medicine and Biology, 2023, 68 (22), pp.225008. ⟨10.1088/1361-6560/ad043d⟩
Article dans une revue irsn-04279218v1
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Cosmic radiation exposure of airline crews in France over the period 2015–2019

Philippe Lestaevel , Christelle Huet , Veronique Lejeune , Carole Moreno , Carmen Villagrasa , et al.
Radioprotection, 2023, 58 (4), pp.317-325. ⟨10.1051/radiopro/2023027⟩
Article dans une revue irsn-04349615v1
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MINAS TIRITH: a new tool for simulating radiation-induced DNA damage at the cell population level

Yann Thibaut , Geraldine Gonon , Juan S Martinez , Michael Petit , Aurelie Vaurijoux , et al.
Physics in Medicine and Biology, 2023, 68 (3), pp.034002. ⟨10.1088/1361-6560/acb196⟩
Article dans une revue hal-03957464v1
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Prediction of DNA rejoining kinetics and cell survival after proton irradiation for V79 cells using Geant4-DNA

Dousatsu Sakata , Ryoichi Hirayama , Wook-Geun Shin , Mauro Belli , Maria Tabocchini , et al.
Physica Medica European Journal of Medical Physics, 2023, 105, pp.102508. ⟨10.1016/j.ejmp.2022.11.012⟩
Article dans une revue hal-03908986v1
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A matter of space: how the spatial heterogeneity in energy deposition determines the biological outcome of radiation exposure

Giorgio Baiocco , Stefan Bartzsch , Valeria Conte , Thomas Friedrich , Burkhard Jakob , et al.
Radiation and Environmental Biophysics, 2022, 61, pp.545-559. ⟨10.1007/s00411-022-00989-z⟩
Article dans une revue irsn-04133922v1
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Lessons learnt from the recent EURADOS intercomparisons in computational dosimetry

Hans Rabus , Maria Zankl , Jose-Maria Gomez-Ros , Carmen Villagrasa , Jonathan Eakins , et al.
Radiation Measurements, 2022, 156, pp.106822. ⟨10.1016/j.radmeas.2022.106822⟩
Article dans une revue irsn-04133994v1
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New cell nucleus geometry for modelling the radiation-induced DNA damage topology

Yann Thibaut , Carmen Villagrasa , S. Incerti , Yann Perrot
International Conférence on Monte Carlo Techniques for Medical Applications, 2022, MCMA2022, Apr 2022, Antwerp, Belgium. pp.129
Communication dans un congrès irsn-03948937v1
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Intercomparison of micro- and nanodosimetry Monte Carlo simulations: An approach to assess the influence of different cross-sections for low-energy electrons on the dispersion of results

Carmen Villagrasa , Hans Rabus , Giorgio Baiocco , Yann Perrot , Alessio Parisi , et al.
Radiation Measurements, 2022, 150, pp.106675. ⟨10.1016/j.radmeas.2021.106675⟩
Article dans une revue hal-03508915v1
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Intercomparison of nanodosimetric distributions in nitrogen simulated with Geant4 and PTra track structure codes

Marcin Pietrzak , Heidi Nettelbeck , Yann Perrot , Carmen Villagrasa , Aleksandr Bancer , et al.
Physica Medica European Journal of Medical Physics, 2022, 102, pp.103-109. ⟨10.1016/j.ejmp.2022.09.003⟩
Article dans une revue hal-03811358v1
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Nanodosimetric calculations of radiation-induced DNA damage in a new nucleus geometrical model based on the isochore theory

Yann Thibaut , Nicolas Tang , Hoang Ngoc Tran , Aurelie Vaurijoux , Carmen Villagrasa , et al.
International Journal of Molecular Sciences, 2022, 23 (7), pp.3370. ⟨10.3390/ijms23073770⟩
Article dans une revue hal-03636006v1
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Modeling early radiation DNA damage occurring during [177Lu]-DOTATATE Radionuclide Therapy

Giulia Tamborino , Yann Perrot , Marijke de Saint-Hubert , Lara Struelens , Julie Nonnekens , et al.
Journal of Nuclear Medicine, 2022, 63 (5), pp.761-769. ⟨10.2967/jnumed.121.262610⟩
Article dans une revue hal-03731239v1

Review of the Geant4-DNA Simulation Toolkit for Radiobiological Applications at the Cellular and DNA Level

Ioanna Kyriakou , Dousatsu Sakata , Hoang Ngoc Tran , Yann Perrot , Wook-Geun Shin , et al.
Cancers, 2022, 14 (1), pp.35. ⟨10.3390/cancers14010035⟩
Article dans une revue hal-03501436v1
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DNA damage modeled with Geant4-DNA: effects of plasmid DNA conformation and experimental conditions

N D-Kondo , E Moreno-Barbosa , V Štěphán , K Stefanová , Yann Perrot , et al.
Physics in Medicine and Biology, 2021, 66 (24), pp.245017. ⟨10.1088/1361-6560/ac3a22⟩
Article dans une revue hal-03501427v1
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Modelling the topology of radiation-induced damage at the cell population level.

Yann Thibaut , Carmen Villagrasa , Sébastien Incerti , Yann Perrot
46th Annual Meeting of the European Radiation Research Society, ERRS 2021, Nov 2021, CAEN, France. 2021
Poster de conférence hal-03513510v1
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Isochore Nuclear Geometry for modeling the radiation-induced DNA damage toplogy

Yann Thibaut , Carmen Villagrasa , Sébastien Incerti , Yann Perrot
46th Annual Meeting of the European Radiation Research Society, ERRS 2021, Nov 2021, CAEN, France. 2021
Poster de conférence hal-03505857v1

A Geant4-DNA Evaluation of Radiation-Induced DNA Damage on a Human Fibroblast

Wook-Geun Shin , Dousatsu Sakata , Nathanael Lampe , Oleg Belov , Ngoc Hoang Tran , et al.
Cancers, 2021, 13 (19), pp.4940. ⟨10.3390/cancers13194940⟩
Article dans une revue hal-03363166v1
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TOPAS-nBio validation for simulating water radiolysis and DNA damage under low-LET irradiation

J Ramos-Méndez , J Laverne , N Domínguez-Kondo , J Milligan , V Štěpán , et al.
Physics in Medicine and Biology, 2021, 66 (17), pp.175026. ⟨10.1088/1361-6560/ac1f39⟩
Article dans une revue hal-03334498v1
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Geant4-DNA simulation of the pre-chemical stage of water radiolysis and its impact on initial radiochemical yields

Wook-Geun Shin , Jose Ramos-Mendez , Ngoc Hoang Tran , Shogo Okada , Yann Perrot , et al.
Physica Medica European Journal of Medical Physics, 2021, 88, pp.86 - 90. ⟨10.1016/j.ejmp.2021.05.029⟩
Article dans une revue hal-03273596v1
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Consistency checks of results from a Monte Carlo code intercomparison for emitted electron spectra and energy deposition around a single gold nanoparticle irradiated by X-rays

Hans Rabus , Weibo Li , Heidi Nettelbeck , Jan Schuemann , Carmen Villagrasa , et al.
Radiation Measurements, 2021, 147, pp.106637. ⟨10.1016/j.radmeas.2021.106637⟩
Article dans une revue hal-03550119v1
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Radiation Enhancer Effect of Platinum Nanoparticles in Breast Cancer Cell Lines: In Vitro and In Silico Analyses

Marie Hullo , Romain Grall , Yann Perrot , Cécile Mathe , Véronique Menard , et al.
International Journal of Molecular Sciences, 2021, 22, pp.4436. ⟨10.3390/ijms22094436⟩
Article dans une revue hal-03550120v1
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Intercomparison of Monte Carlo calculated dose enhancement ratios for gold nanoparticles irradiated by X-rays: Assessing the uncertainty and correct methodology for extended beams

H. Rabus , W.B. Li , C. Villagrasa , J. Schuemann , P.A. Hepperle , et al.
Physica Medica European Journal of Medical Physics, 2021, 84, pp.241-253. ⟨10.1016/j.ejmp.2021.03.005⟩
Article dans une revue hal-03257934v1

Radiochimie et chimie sous rayonnement - rayonnements ionisants et radioéléments Le code Geant4-DNA :simuler les premiers instants de la radiolyse de l’eau

Wook Geun Shin , Ngoc Hoang Tran , Jose Ramosmendez , Yann Perrot , Gerard Montarou , et al.
L'Actualité Chimique, 2021, 460-461, pp.29-33
Article dans une revue cea-03187662v1
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Assessment of DNA damage with an adapted independent reaction time approach implemented in Geant4‐DNA for the simulation of diffusion‐controlled reactions between radio‐induced reactive species and a chromatin fiber

Hoang Ngoc Tran , José Ramos‐méndez , Wook‐geun Shin , Yann Perrot , Bruce Faddegon , et al.
Medical Physics, 2021, 48 (2), pp.890-901. ⟨10.1002/mp.14612⟩
Article dans une revue hal-03149166v1
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Quality assurance for the use of computational methods in dosimetry: activities of EURADOS Working Group 6 “Computational Dosimetry”

Hans Rabus , Jose-Maria Gomez-Ros , C. Villagrasa , J. Eakins , Thomas Vrba , et al.
Journal of Radiological Protection, In press, ⟨10.1088/1361-6498/abd914⟩
Article dans une revue cea-03136483v1
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Independent reaction times method in Geant4‐DNA: Implementation and performance

Jose Ramos-Mendez , Wook‐geun Shin , Mathieu Karamitros , Jorge Domínguez‐kondo , Ngoc Hoang Tran , et al.
Medical Physics, 2020, 47 (11), pp.5919-5930. ⟨10.1002/mp.14490⟩
Article dans une revue hal-02988428v2
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Requirements of modelling tools for the understanding of radiation-induced biological damage at the cellular level

Yann Perrot , Carmen Villagrasa
Technical Meeting on New Trends and Advances in Microdosimetry and its Applications (Virtual Event), AIEA, Oct 2020, Vienne (E-conference), Austria
Communication dans un congrès irsn-04134012v1
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Measurement of out-of-field dose to the uterus during proton therapy of the head and neck

J. Le Guevelou , F. Trompier , C. Villagrasa , A. Vela , A. Isambert , et al.
Cancer/Radiothérapie, 2020, 24 (2), pp.138 - 142. ⟨10.1016/j.canrad.2019.10.004⟩
Article dans une revue hal-03490292v1
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Intercomparison of dose enhancement ratio and secondary electron spectra for gold nanoparticles irradiated by X-rays calculated using multiple Monte Carlo simulation codes

W. B. Li , A. Belchior , M. Beuve , Y. Z. Chen , S. Di Maria , et al.
Physica Medica European Journal of Medical Physics, 2020, 69, pp.147-163. ⟨10.1016/j.ejmp.2019.12.011⟩
Article dans une revue hal-02452613v1
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Biological measure of DNA damage after single-ion microbeam irradiation and Monte Carlo simulations

Geraldine Gonon , Carmen Villagrasa , Pascale Voisin , Sylvain Meylan , Mohamedamine Benadjaoud , et al.
16th International Congress of Radiation Research ICRR 2019, Aug 2019, MANCHESTER, France. 2019
Poster de conférence hal-02635559v1
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Determining dose enhancement factors of high-Z nanoparticles from simulations where lateral secondary particle disequilibrium exists

Hans Rabus , Elisabetta Gargioni , Wei Bo Li , Heidi Nettelbeck , Carmen Villagrasa
Physics in Medicine and Biology, 2019, 64 (15), pp.155016. ⟨10.1088/1361-6560/ab31d4⟩
Article dans une revue hal-02524795v1