: one haploid set of chromosomes with the genes they contain
broadly
: the genetic material of an organism compare proteome
Examples of genome in a Sentence
Recent Examples on the Web
Orchid’s approach involves whole genome sequencing, and expands on traditional screening by sequencing nearly all of an embryo’s genome.
—
Amanda Gerut, Fortune, 29 Nov. 2025
For the new research, the scientists analyzed samples of nuclear DNA—the main genome of an organism, containing both parents’ contributions—from the same specimens that were examined in the older study, which had not looked at this type of DNA.
—Meghan Bartels, Scientific American, 27 Nov. 2025
The researchers pinpointed a part of the bird flu genome that helps the virus thrive in this warm environment, called PB1.
—NPR, 27 Nov. 2025
To find out more, the team analyzed thousands of dog and wolf genomes in publicly available databases.
—CBS News, 25 Nov. 2025
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“Genome.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/genome. Accessed 9 Dec. 2025.
Medical Definition
genome
noun
ge·nome
ˈjē-ˌnōm 
: one haploid set of chromosomes with the genes they contain
broadly
: the genetic material of an organism
The idea behind sequencing an organism's genome—decoding, letter by letter, the message contained in every last one of its genes—is that it would tell us a lot about how the organism works. —Lori Oliwenstein, Discover
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