Toward increased utility of mtDNA in forensic identifications
RS Just, JA Irwin, JE O'Callaghan, JL Saunier… - Forensic science …, 2004 - Elsevier
The utility of mtDNA in forensic identifications is limited by its low power of discrimination
and the absence of high quality mtDNA databases. Single nucleotide polymorphisms
(SNPs) in the control region outside of hypervariable regions I and II (HVI/HVII), and in the
coding region of the mtDNA genome, can provide additional discrimination in mtDNA
testing. We have identified particularly useful SNP sites via high throughput sequencing of
the entire mtDNA genome. We report here two cases in which an 11-plex SNP assay (panel …
and the absence of high quality mtDNA databases. Single nucleotide polymorphisms
(SNPs) in the control region outside of hypervariable regions I and II (HVI/HVII), and in the
coding region of the mtDNA genome, can provide additional discrimination in mtDNA
testing. We have identified particularly useful SNP sites via high throughput sequencing of
the entire mtDNA genome. We report here two cases in which an 11-plex SNP assay (panel …
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